Work

In vitro activity of moxalactam alone and in combination with penicillin against common meningeal pathogens

Year: 1982

Type: article

Abstract: Moxalactam demonstrated marked activity against beta-lactamase-positive and -negative Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis by both standard minimal inhibitory concentration testing and growth curve studies. Moxalactam was ineffective against S. pneumoniae partially susceptible to penicillin G. Moxalactam (5 micrograms/ml) and penicillin (1 microgram/ml) in combination were indifferent to each other's antibacterial activity, exerting neither synergism nor antagonism against these organisms.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.21.3.521

Authors: P H Azimi, M G Dunphy

Language: English

Topic: Antibiotics Pharmacokinetics and Efficacy

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2044668253

FWCI: 0.812

Cites: 13

Cited by: 3

Related to: 10