Work

Microglia: Scapegoat, Saboteur, or Something Else?

Year: 2013

Type: review

Abstract: Microglia are resident immune cells in the brain and spinal cord. These cells provide immune surveillance and are mobilized in response to disparate diseases and injuries. Although microglial activation is often considered neurotoxic, microglia are essential defenders against many neurodegenerative diseases. It also seems increasingly likely that microglial dysfunction can underlie certain neurological diseases without an obvious immune component.

Source: Science

DOI: 10.1126/science.1227901

Authors: Adriano Aguzzi, Ben A. Barres, Mariko L. Bennett

Institutions: University Hospital Zurich, Stanford Medicine, Stanford University

Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Neurological Disorders and Stroke