Work

Microfluidics without pumps: reinventing the T-sensor and H-filter in paper networks

Year: 2010

Type: article

Abstract: Conventional microfluidic devices typically require highly precise pumps or pneumatic control systems, which add considerable cost and the requirement for power. These restrictions have limited the adoption of microfluidic technologies for point-of-care applications. Paper networks provide an extremely low-cost and pumpless alternative to conventional microfluidic devices by generating fluid transport through capillarity. We revisit well-known microfluidic devices for hydrodynamic focusing, sized-based extraction of molecules from complex mixtures, micromixing, and dilution, and demonstrate that paper-based devices can replace their expensive conventional microfluidic counterparts.

Source: Lab on a Chip

DOI: 10.1039/c004821f

Authors: Jennifer L. Osborn, Barry Lutz, Elain Fu, Peter Kauffman, Dean Y. Stevens, Paul Yager

Institution: University of Washington

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, National Institute of Biomedical Imaging and Bioengineering

Award: A sensitive multiplexed diagnostic platform using disposable 2D paper networks