Work

The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak

Year: 2014

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2014.12.072

Authors: Wei Qian, Joseph Salamoun, Jingnan Wang, Vera Roginskaya, Bennett Van Houten, Peter Wipf

Institutions: University of Pittsburgh, UPMC Hillman Cancer Center, Tsinghua University

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Pennsylvania Department of Health, China Scholarship Council, National Cancer Institute, National Institute of General Medical Sciences

Awards: New Concepts, Methodologies and Scaffolds for Diversity-Oriented Organic Synthes, SPORE in Skin Cancer, G5785919769, Head and Neck Cancer SPORE, Cancer Center Support Grant

OpenAlex ID: W2045986149

FWCI: 1.384

Cites: 45

Cited by: 15

Related to: 10