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Characterization of NcsB2 as a Promiscuous Naphthoic Acid/Coenzyme A Ligase Integral to the Biosynthesis of the Enediyne Antitumor Antibiotic Neocarzinostatin

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Year: 2007
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/ja071886a
Authors: Heather A. Cooke, Jian Zhang, Meghan A. Griffin, Koichi Nonaka, Steven G. Van Lanen, Ben Shen, Steven D. Bruner
Institutions: Boston College, University of Wisconsin–Madison
Language: English

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences

Open Access status: closed

Funders: National Cancer Institute, National Institute of Allergy and Infectious Diseases
Awards: UWCCC National Cooperative Drug Discovery Group for Can*, Enediyne Biosynthesis and Engineering, G2271657281, Characterization of C-1027 Enediyne Polyketide Synthase, G3053038336, G5977718968, Enediyne Antitumor Antibiotic Synthesis - Streptomycetes
OpenAlex ID: W2046178944
FWCI: 1.553
Cites: 10
Cited by: 26
Related to: 10
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