Work

Identification of Asm19 as an Acyltransferase Attaching the Biologically Essential Ester Side Chain of Ansamitocins Using N-Desmethyl-4,5-desepoxymaytansinol, Not Maytansinol, as Its Substrate

Year: 2002

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/ja020214b

Authors: Steven J. Moss, Linquan Bai, Sabine Toelzer, Brian J. Carroll, Taifo Mahmud, Tin-Wein Yu, Heinz G. Floss

Institution: University of Washington

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: closed

Funder: National Cancer Institute

Awards: Biosynthesis of Maytansinoids and Analogs, G4367561413

OpenAlex ID: W2046357515

FWCI: 1.413

Cites: 8

Cited by: 51

Related to: 10