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Targeting DXP synthase in human pathogens: enzyme inhibition and antimicrobial activity of butylacetylphosphonate

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Year: 2013
Type: article
Source: The Journal of Antibiotics
DOI: 10.1038/ja.2013.105
Authors: Jessica M Smith, Nicole V Warrington, Ryan J Vierling, Misty L Kuhn, Wayne F Anderson, Andrew T Koppisch, Caren L Freel Meyers
Institutions: Johns Hopkins University, Northern Arizona University, Northwestern University
Language: English

Topic: Plant biochemistry and biosynthesis
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: G2933538316, G2934285047, G3272075477, Biochemistry, Cellular and Molecular Biology Program, G4336488413, Targeting Non-mammalian Isoprenoid Biosynthesis, G6601593777, G7312179196, G735636076, G7505410320, Targeting a Unique Enzyme Mechanism in Non-Mammalian Isoprenoid Biosynthesis, The Chemistry-Biology Interface Program at Johns Hopkins University, The Robert H. Lurie Comprehensive Cancer Center
OpenAlex ID: W2046424095
FWCI: 2.089
Cites: 56
Cited by: 45
Related to: 10
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