Work

Control of dorsoventral patterning of somitic derivatives by notochord and floor plate.

Year: 1993

Type: article

Abstract: We have examined the effect of implantation of a supernumerary notochord or floor plate on dorsoventral somitic organization. We show that notochord and floor plate are able to inhibit the differentiation of the dorsal somitic derivatives--i.e., axial muscles and dermis--thus converting the entire somite into cartilage, which normally arises only from its ventral part. We infer from these results that the dorsoventral patterning of somitic derivatives is controlled by signals provided by ventral axial structures.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.90.11.5242

Authors: O Pourquié, M Coltey, M A Teillet, C Ordahl, N M Le Douarin

Institution: Centre National de la Recherche Scientifique

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2046560478

FWCI: 8.495

Cites: 23

Cited by: 308

Related to: 10