Work

Modeling In Vivo Pharmacokinetics and Pharmacodynamics of Moxifloxacin Therapy forMycobacterium tuberculosisInfection by Using a Novel Cartridge System

Year: 2005

Type: article

Abstract: To study the efficacy of moxifloxacin treatment for tuberculosis, we utilized a novel cartridge system to simulate in vivo pharmacokinetics. We found this system to be a robust method for modeling in vivo pharmacokinetics and present data supporting the utility of intermittent moxifloxacin treatment as a component of antituberculosis chemotherapy.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.49.2.853-856.2005

Authors: Amy Sarah Ginsburg, Jin Lee, Samuel C. Woolwine, Jacques H. Grosset, Fayez M. Hamzeh, William R. Bishai

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases