Work

Trypanosomatidae codon usage and GC distribution

Year: 1992

Type: article

Abstract: A study of Trypanosomatidae GC distribution and codon usage is presented. The codon usage patterns in coincidence with the phylogenetical data are similar in Crithidia and Leishmania, whereas they are more divergent in Trypanosoma brucei and T. cruzi. The analysis of the GC mutational pressure in these organisms reveals that T. brucei, and to a lesser extent T. cruzi, have evolved towards a more balanced use of all bases, whereas Leishmania and Crithidia retain features of a primeval genetic apparatus. Tables with the approximated GC mutational pressure in homologous genes, and codon usage in Trypanosomatidae are presented.

Source: Memórias do Instituto Oswaldo Cruz

DOI: 10.1590/s0074-02761992000400009

Authors: Guilhermina Alonso, Palmira Guevara, Jose L. Ramirez

Institution: Universidad Central de Venezuela

Language: English

Topic: Trypanosoma species research and implications

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

Open Access status: diamond

OpenAlex ID: W2047358379

FWCI: 1.42

Cites:

Cited by: 25

Related to: 10