Synthesis of 2-Phenyl-2,3,4,5-tetrshydro-1-benzoxepin-5-ones
Year: 1990
Type: article
Abstract: A series of 2-phenyl-2,3,4,5-tetrahydro-1-benzoxepin--ones were synthesized by 2 steps from flavones through 3.4-benzo-5-0x0-2-ombicyclo[4.1.Olheptanes.As part of an effort to offer useful frameworks for the purpose of synthesis of pharmacologically active compounds.we have prepared a series of 2-phenyl-2,3,4,5tetrahydro-1-benzoxepin-5-ones(1) by two steps through cyclopropanations of flavanes followed by Pereyre's reductive cleavage of the bicyclic ring syst-.A large number of benzoxepin derivatives have been synthesized to investigate their
Source: Heterocycles
DOI: 10.3987/com-89-s53
Institution: Suntory (Japan)
Language: German
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2047887414