Work

Electrical performance of penetrating microelectrodes chronically implanted in cat cortex

Year: 2011

Type: conference-paper

Abstract: Penetrating multielectrode arrays with electrode coatings of sputtered iridium oxide (SIROF) have been implanted chronically in cat cortex for periods over 300 days. The ability of these electrodes to inject charge at levels above expected thresholds for neural excitation has been examined in vivo by measurements of voltage transients in response to current-controlled, cathodal stimulation pulsing. The effect of current pulse width from 150 μs to 500 μs and voltage biasing of the electrodes in the interpulse period at two levels, 0.0 V and 0.6 V vs. Ag|AgCl, were also investigated. The results of in vivo characterization of the electrodes by open-circuit potential measurements, cyclic voltammetry and impedance spectroscopy are also reported.

Source: Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

DOI: 10.1109/iembs.2011.6091339

Authors: S. R. Kane, S. F. Cogan, J. Ehrlich, T. D. Plante, D. B. McCreery

Institutions: EIC Laboratories, Huntington Medical Research Institutes

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Neurological Disorders and Stroke

Award: Functionalized Coatings for Enhanced Neural Interfaces