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Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells

Year: 2013
Type: article
Abstract: Meeting abstracts Host conditioning with total body irradiation (TBI) can potently augment adoptive T cell (ACT) immunotherapies by removal of sinks for homeostatic cytokines such as IL-7 and IL-15, depletion of CD4+ Tregs, and liberation of endogenous toll like-receptor agonists. Clinically, TBI-
DOI: 10.1186/2051-1426-1-s1-p121
Authors: Christopher A Klebanoff, Sean Spencer, Rahu Roychoudhuri, Yun Ji, Madhu Sukumar, Pawel Muranski, Joseph L Napoli, Luca Gattinoni, Yasmine Belkaid, Nicholas P Restifo
Language: English
Subfield: Immunology
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2048442441
FWCI:
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