Work

Backbone modification of a polypeptide drug alters duration of action in vivo

Year: 2014

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.2920

Authors: Ross W Cheloha, Akira Maeda, Thomas Dean, Thomas J Gardella, Samuel H Gellman

Institutions: University of Wisconsin–Madison, Harvard University, Massachusetts General Hospital

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Public Health Service, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases

Awards: Novel Agonists and Inverse Agonists for B-Family GPCRs, G2330373010, Hormonal Control of Calcium Metabolism, Biotechnology Training Program, Structural and Functional Mechanisms of PTH-Receptor Signaling, CENTER FOR SKELETAL RESEARCH

OpenAlex ID: W2048553889

FWCI: 8.197

Cites: 20

Cited by: 125

Related to: 10