Year: 1980
Type: article
Study design: Observational Study
Abstract: Hydroxykynurenine/hydroxyanthranilic acid ratios were measured in children with febrile convulsions, afebrile fits, and fever, as well as in healthy controls. Increased ratios were found not only in the children who had fits but also in the children who were febrile and did not have fits. It is suggested that a raised hydroxykynurenine/hydroxyanthranilic acid ratio does not necessarily indicate vitamin B6 deficiency but may represent a nonspecific response of tryptophan metabolism to stress.
Source: Archives of Disease in Childhood
Authors: J McKiernan, D Mellor, S Court, J Edson, K Lacey
Institutions: University Hospital Limerick, Queen's Medical Centre
Language: English
Subfield: Biological Psychiatry
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2048703694