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Seizure‐induced basal dendrites on granule cells

Year: 2010
Type: article
Abstract: Summary Seizure‐induced hilar basal dendrites on dentate granule cells are observed in several rodent models of temporal lobe epilepsy. Ultrastructural evidence showed that basal dendrites receive predominantly excitatory synapses, including many from mossy fibers. Such highly interconnected granule cells with basal dendrites are suggested to enhance hyperexcitability within the dentate network. For an expanded treatment of this topic see Jasper’s Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado‐Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at http://www.ncbi.nlm.nih.gov/books ).
Source: Epilepsia
DOI: 10.1111/j.1528-1167.2010.02829.x
Authors: Charles E. Ribak, Lee A. Shapiro, Xiao‐Xin Yan, Khashayar Dashtipour, J. Victor Nadler, Andre Obenaus, Igor Spigelman, Paul S. Buckmaster
Institutions: University of California, Irvine, Texas A&M University, Southern Illinois University Carbondale, Loma Linda University, Duke University, University of California, Los Angeles, Stanford University
Language: English
Field: Medicine
Open Access status: bronze
OpenAlex ID: W2048713850
FWCI:
Cites: 4
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Related to: 10