Inactivation and proteolytic cleavage of phage lambda repressor in vitro in an ATP-dependent reaction.
Year: 1977
Type: article
Abstract: We have reproduced in vitro the inactivation of bacteriophage lambda repressor that occurs in vivo when a lambda lysogen is treated with agents such as ultraviolet radiation that attack DNA. ATP and a divalent cation are required for the inactivation reaction. The ind- repressor is insensitive to the inactivation mechanism. A proteolytic cleavage of repressor accompanies inactivation in vitro, as it does in vivo.
Authors: J W Roberts, C W Roberts, D W Mount
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2048869154