Work

Chronic Wasting Disease Agents in Nonhuman Primates

Year: 2014

Type: article

Abstract: Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.

Source: Emerging infectious diseases

DOI: 10.3201/eid2005.130778

Authors: Brent Race, Kimberly D. Meade-White, Katie Phillips, James Striebel, Richard Race, Bruce Chesebro

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Prion Diseases and Protein Misfolding

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases