Work

Biomedical Applications: Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer‐Functionalized Gold Nanostars (Adv. Mater. 22/2013)

Year: 2013

Type: article

Abstract: Chlorin e6-conjugated gold nanostars (GNSPEG-Ce6) are constructed by X. Chen, G. Lu, and co-workers on page 3055 as a novel theranostic system for imaging, and photodynamic and photothermal therapy. Utilizing the difference in photostability between chlorin e6 and gold nanostars, GNS-PEG-Ce6 can coordinate the early-phase photodynamic effect with the late-phase photothermal effect upon single wavelength continuous wave laser irradiation. With significantly improved anti-cancer efficacy and simplified treatment process, the GNS-PEGCe6 formula shows high potential for translation into clinical practice to treat cancer patients.

Source: Advanced Materials

DOI: 10.1002/adma.201370142

Authors: Shouju Wang, Peng Huang, Liming Nie, Ruijun Xing, Dingbin Liu, Zhe Wang, Jing Lin, Shouhui Chen, Gang Niu, Guangming Lu, Xiaoyuan Chen

Institutions: National Institutes of Health, Nanjing General Hospital of Nanjing Military Command, National Institute of Biomedical Imaging and Bioengineering, Nanjing University, Shanghai Jiao Tong University, Xiamen University

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2050046830

FWCI: 0.736

Cites:

Cited by: 11

Related to: 10