Year: 1995
Type: review
Abstract: Carbohydrate-binding proteins (lectins) are widespread among prokaryotes and eucaryotes. Among the latter, lectins mediate many specific biological functions including cell-cell interactions, protein trafficking, and primitive defense reactions(1, 2, 3, 4, 5, 6). We describe here a newly recognized family of mammalian lectins belonging to the immunoglobulin superfamily (IgSF)11 (7, 8). Relative emphasis is placed on a prototypic member, CD22. Previously known mammalian lectins can be classified into distinct families based on protein sequence homologies (1) ().
Source: Journal of Biological Chemistry
Authors: Leland D. Powell, Ajit Varki
Institutions: University of California San Diego, Moores Cancer Center
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W2050117679