Work

Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity

Year: 2005

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm040159c

Authors: Hwei-Ru Tsou, Elsebe G. Overbeek-Klumpers, William A. Hallett, Marvin F. Reich, M. Brawner Floyd, Bernard D. Johnson, Ronald S. Michalak, Ramaswamy Nilakantan, Carolyn Discafani, Jonathan Golas, Sridhar K. Rabindran, Ru Shen, Xiaoqing Shi, Yu-Fen Wang, Janis Upeslacis, Allan Wissner

Institution: Wyeth

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2050156776

FWCI: 6.03

Cites: 22

Cited by: 303

Related to: 9

Parts: 1