Work

Combined Ultrasonic Thermal Ablation with Interleaved ARFI Image Monitoring Using a Single Diagnostic Curvilinear Array: A Feasibility Study

Year: 2011

Type: article

Abstract: The goal of this work is to demonstrate the feasibility of using a diagnostic ultrasound system (Siemens Antares and CH6-2 curvilinear array) to ablate ex vivo liver with a custom M-mode sequence and monitor the resulting tissue stiffening with 2-D Acoustic Radiation Force Impulse (ARFI) imaging. Images were taken before and after ablation, as well as in 5- s intervals during the ablation sequence in order to monitor the ablation lesion formation temporally. Ablation lesions were generated at depths up to 1.5 cm from the surface of the liver and were not visible in B-mode. ARFI images showed liver stiffening with heating that corresponded to discolored regions in gross pathology. As expected, the contrast of ablation lesions in ARFI images is observed to increase with ablation lesion size. This study demonstrated the ability of a diagnostic system using custom beam sequences to localize an ablation site, heat the site to the point of irreversible damage and monitor the formation of the ablation lesion with ARFI imaging.

Source: Ultrasonic Imaging

DOI: 10.1177/016173461103300402

Authors: Kristin Frinkley Bing, Ned C. Rouze, Mark L. Palmeri, Veronica M. Rotemberg, Kathryn R. Nightingale

Institutions: Georgia Tech Research Institute, Duke University

Language: English

Topic: Ultrasound Imaging and Elastography

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Siemens Medical Solutions USA, National Institutes of Health, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering