Work

T-Cell Replete Peripheral Blood Stem Cell Transplantation after Non-Myeloablative Conditioning with Post-Transplant High Dose Cyclophosphamide Is Safe and Is Associated with Acceptable Outcomes

Year: 2014

Type: article

Abstract: Multiple approaches have been made to minimize graft versus host disease (GvHD) after allogeneic hematopoietic cell transplantation (allo-HCT) without compromising graft versus leukemia (GvL) effect. Use of high dose cyclophosphamide in the early post-transplant period (PT-Cy) has significantly improved the outcomes of allo-HCT and encouraging results using this regimen have been recently reported in both haploidentical and non-haploidentical transplant setting (Bashey et al JCO, 2013, Fuchs et al, Blood, 2010).

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2013.12.014