Work

Staphylolytic Enzyme from Chalaropsis : Mechanism of Action

Year: 1964

Type: article

Abstract: The staphylolytic enzyme recently isolated from cultures of a Chalaropsis species by Hash is shown to be an acetylmurainidase that cleaves all the glycosidic linkages of N-acetylmuramic acid and N,O-diacetylmuramic acid in the cell wall of Staphylococcus aureus strain Copenhagen. It is similar in specificity to the "32 enzyme" from Streptomyces albus but it differs from egg-white lysozyme whose activity is inhibited by the presence of O-acetyl groups.

Source: Science

DOI: 10.1126/science.146.3645.781

Authors: Donald J. Tipper, Jack L. Strominger, Jean-Marie Ghuysen

Institutions: University of Wisconsin System, University of Wisconsin–Madison, University of Liège

Language: English

Topic: Enzyme Production and Characterization

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2050869411

FWCI: 13.24

Cites: 5

Cited by: 50

Related to: 10