Work

American ginseng modulates pancreatic beta cell activities

Year: 2007

Type: article

Abstract: The mechanism of the beneficial effects of Panax quinquefolius (Xiyangshen, American ginseng) on diabetes is yet to be elucidated. Recent studies show that Panax quinquefolius increases insulin production and reduces the death of pancreatic beta cells. Mechanism studies indicate that Panax quinquefolius improves cell's immuno-reactivity and mitochondrial function through various factors. Clinical studies show that Panax quinquefolius improves postprandial glycemia in type 2 diabetic patients. Further studies to identify the component(s) of Panax quinquefolius linked with pancreatic islets/beta cells in vitro and in vivo are warranted for better understanding of the full effects of Panax quinquefolius.

Source: Chinese Medicine

DOI: 10.1186/1749-8546-2-11

Authors: Zonggui Wu, John Zeqi Luo, Luguang Luo

Institutions: Second Military Medical University, Shanghai Changzheng Hospital, Brown University, Roger Williams Medical Center

Language: English

Topic: Ginseng Biological Effects and Applications

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990