Work

DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Radical Scavenging Activity of Flavonoids Obtained from Some Medicinal Plants.

Year: 2001

Type: article

Abstract: A reactive oxygen species has been implicated in a range of human pathological diseases such as atherosclerosis and certain cancers. Flavonoids are reported to exhibit various biological activities, including antioxidative and free radical scavenging activities. Several flavonoids obtained from barley leaves, soybean and some medicinal plants, Silybum marianum, Sophorae Flos, Cinnamon, Ephedrae Herba and Scutellariae Radix, were tested for their DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. The structure-activity relationships suggested that not only the numbers of hydroxy group but also the position of hydroxy group might be important for mediating potent activity.

Source: Biological and Pharmaceutical Bulletin

DOI: 10.1248/bpb.24.1202

Authors: Masafumi OKAWA, Junei KINJO, Toshihiro NOHARA, Masateru ONO

Institutions: Kumamoto University, Fukuoka University, Kyushu Tokai University

Language: English

Topic: Phytochemicals and Antioxidant Activities

Subfield: Biochemistry (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2051180867

FWCI: 1.839

Cites: 16

Cited by: 320

Related to: 9