Work

Functional MRI of Macaque Monkeys Performing a Cognitive Set-Shifting Task

Year: 2002

Type: article

Abstract: Functional brain organization of macaque monkeys and humans was directly compared by functional magnetic resonance imaging. Subjects of both species performed a modified Wisconsin Card Sorting Test that required behavioral flexibility in the form of cognitive set shifting. Equivalent visual stimuli and task sequence were used for the two species. We found transient activation related to cognitive set shifting in focal regions of prefrontal cortex in both monkeys and humans. These functional homologs were located in cytoarchitectonically equivalent regions in the posterior part of ventrolateral prefrontal cortex. This comparative imaging provides insights into the evolution of cognition in primates.

Source: Science

DOI: 10.1126/science.1067653

Authors: Kiyoshi Nakahara, Toshihiro Hayashi, Seiki Konishi, Yasushi Miyashita

Institutions: The University of Tokyo, National Institute for Physiological Sciences

Language: English

Topic: Neural and Behavioral Psychology Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2051511819

FWCI: 10.22

Cites: 27

Cited by: 285

Related to: 10