Work

Cancer Risk Assessment at the Atomic Level

Year: 2006

Type: article

Abstract: A flurry of articles on the structure of different domains of BRCA1 and BRCA2 have not only shed light on the biology of these proteins but have also raised hopes that these data could eventually be used to infer cancer association for a large number of inherited missense mutations whose effect on protein function is unclear.

Source: Cancer Research

DOI: 10.1158/0008-5472.can-05-3034

Authors: Alvaro N.A. Monteiro, Fergus J. Couch

Institutions: Moffitt Cancer Center, Mayo Clinic

Language: English

Topic: BRCA gene mutations in cancer

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Breast Cancer Research Foundation, National Institutes of Health, National Cancer Institute