Work

Complementary addressed reagents carrying EDTA‐Fe(II) groups for directed cleavage of single‐stranded nucleic acids

Year: 1984

Type: article

Abstract: An octathymidylate derivative carrying an EDTA residue at its 5'‐terminus was synthesized. In the presence of Fe2+, O2 and dithiotreitol, this derivative cleaves poly(dA) and poly(A) more efficiently than the non‐complementary polynucleotide poly(dT).

Source: FEBS Letters

DOI: 10.1016/0014-5793(84)80869-8

Authors: A.S. Boutorin, V.V. Vlassov, S.A. Kazakov, I.V. Kutiavin, M.A. Podyminogin

Institution: Novosibirsk Institute of Organic Chemistry

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2052380365

FWCI: 1.331

Cites: 11

Cited by: 66

Related to: 10