Work

Distribution, regulation and role of the agmatine deiminase system in mutans streptococci

Year: 2008

Type: article

Abstract: The agmatine deiminase system (AgDS) was identified in seven strains of mutans streptococci. Genes encoding the AgDS of Streptococcus rattus FA-1 were sequenced and found to share homology with the agu genes of Streptococcus mutans UA159. With the exception of Streptococcus sobrinus, the AgDS of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. Agmatine inhibited bacterial growth, suggesting that the AgDS degrades a deleterious substance into useful compounds.

Source: Oral Microbiology and Immunology

DOI: 10.1111/j.1399-302x.2008.00459.x

Authors: A. R. Griswold, M. M. Nascimento, R. A. Burne

Institution: University of Florida

Language: English

Topic: Polyamine Metabolism and Applications

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Dental and Craniofacial Research