Anoxia pretreatment protects soybean cells against H2O2‐induced cell death: possible involvement of peroxidases and of alternative oxidase
Year: 2000
Type: article
Abstract: Anoxia followed by reoxygenation causes extensive damage to cellular components through generation of reactive oxygen intermediates. We examined cellular responses to oxidative stress after anoxia in cultured soybean or human fibroblast cells. Anoxia pretreatment protected soybean but not fibroblasts against H(2)O(2) concentrations that induced programmed cell death in normoxic cells. H(2)O(2) removal in anoxia-pretreated soybean cultures was faster. Protection was associated with increased action of alternative oxidase (AOX) and peroxidases. AOX inhibitors abolished the protective effect, while induction of AOX protected normoxic cells against H(2)O(2). We propose that during anoxia, plant cells can prepare for reoxygenation injury by up-regulating their antioxidant capacity, and that AOX is involved in this process.
Source: FEBS Letters
Authors: Yehudit Amor, Mordechai Chevion, Alex Levine
Institution: Hebrew University of Jerusalem
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: bronze
Funder: Israel Science Foundation
OpenAlex ID: W2052687877