Work

Optical coherence elastography for tissue characterization: a review

Year: 2014

Type: review

Abstract: Optical coherence elastography (OCE) represents the frontier of optical elasticity imaging techniques and focuses on the micro-scale assessment of tissue biomechanics in 3D that is hard to achieve with traditional elastographic methods. Benefit from the advancement of optical coherence tomography, and driven by the increasing requirements in nondestructive biomechanical characterization, this emerging technique recently has experienced a rapid development. In this paper, we start with the description of the mechanical contrast that has been employed by OCE and review the state-of-the-art techniques based on the reported applications and discuss the current technical challenges, emphasizing the unique role of OCE in tissue mechanical characterization. The position of OCE among other elastography techniques.

Source: Journal of Biophotonics

DOI: 10.1002/jbio.201400108

Authors: Shang Wang, Kirill V. Larin

Institutions: Baylor College of Medicine, University of Houston

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Human Genome Research Institute, National Eye Institute

Awards: Biomechanics of early mammalian cardiogenesis, Phenotyping embryonic mammalian heart function using OCT, Consortium for Broad Based Disease Phenotyping of Knockout Mice, Optical Coherence Elastography of the Cornea