Work

QT interval increased after single dose of lofexidine

Year: 2004

Type: article

Abstract: Lofexidine (BritLofex, Britannia) is an α 2 agonist used for opioid detoxification.1 We report one case of an increased QT interval after one dose of 0.4 mg lofexidine.2 A 44 year old white opiate dependent female enrolled in a protocol to assess the safety of taking daily lofexidine with daily methadone. She had no known drug allergies, took no other drugs, and had never taken lofexidine before. An electrocardiogram before …

Source: BMJ

DOI: 10.1136/bmj.329.7474.1075

Authors: John Schmittner, Jennifer R Schroeder, David H Epstein, Kenzie L Preston

Institutions: National Institutes of Health, National Institute on Drug Abuse

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Bupa Foundation