Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography
Year: 2012
Type: article
Abstract: A γ-AApeptide-based tracer for positron emission tomography imaging of integrin α(v)β(3) is reported. Despite its shorter sequence and linear nature, this tracer had comparable integrin α(v)β(3) binding affinity to the cyclic arginine-glycine-aspartic acid peptide but significantly higher resistance to enzymatic degradation and better stability.
Source: Chemical Communications
DOI: 10.1039/c2cc33620k
Authors: Yunan Yang, Youhong Niu, Hao Hong, Haifan Wu, Yin Zhang, Jonathan W. Engle, Todd E. Barnhart, Jianfeng Cai, Weibo Cai
Institutions: University of Wisconsin–Madison, University of South Florida
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Cancer Institute
Award: G42679306
OpenAlex ID: W2053083512