Year: 1990
Type: conference-abstract
Abstract: In recent years, powerful techniques have been developed for the detection of acoustic cavitation produced by short pulses of high-frequency ultrasound. However, quantitative agreement between the measured and theoretically predicted cavitation threshold pressures is poor, presumably because of the lack of a priori knowledge of the mechanism for cavity nucleation. Microbubbles stabilized by human serum albumin have attracted considerable attention as echo-contrast agents in ultrasonography. By seeding clean water with these microbubbles, it is possible both to establish and to control the nucleation mechanism, and thus obtain threshold measurements that can be compared directly with theory. Results from experiments performed at 1 and 2.5 MHz in water seeded with Albunex® stabilized microbubbles (1–1μm in diameter) are presented and compared with theoretical predictions based on a “dirty” bubble model [C. C. Church and R. A. Roy, J. Acoust. Soc. Am. Suppl. 1 86, S41 (1989) ]. [Work supported in part by the ONR and the NIH under Grant No. 2-RO1-CA 39374-04A1.]
DOI: 10.1121/1.2027989
Institution: University of Mississippi
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2053520039