Year: 2007
Type: article
Abstract: Failure of the CD4+CD25+Foxp3+ regulatory T-cell compartment to control immune reactivity to self-antigens leads to the development of chronic graft-versus-host disease largely mediated by donor-derived helper T cells that secrete pro-inflammatory cytokines.
Graft-versus-host disease (GVHD) remains
Source: Blood
Author: Allan D. Hess
Institution: Johns Hopkins University
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2053526848