Year: 2013
Type: article
Abstract: Kinetic assay of seeded growth: The graph shows the variation in intrinsic fluorescence intensity of amyloid fibrils. Fluorescence increases during the seeded aggregation of α-synuclein seeds with α-synuclein monomeric protein (blue curve) but not when α-synuclein seeds are incubated with β-synuclein monomeric protein (black curve), thus showing that no seeded growth occurred in this case.
Source: ChemBioChem
Institution: University of Cambridge
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
Awards: Development of single molecule techniques for nanoscale imaging of toxic protein species in vitro and in cells., Mechanisms of neurotoxicity of amyloid aggregates., Next generation live super-resolution microscopy: development and application at the Cambridge Advanced Imaging Centre, G8039008064, Mechanisms of neurotoxicity of amyloid aggregates
OpenAlex ID: W2054056155