Blocked 5′-termini in the fragments of chromosomal DNA produced in cells exposed to the antitumour drug 4′-[(9-acridinyl)-amino]methanesulphon-m-anisidide (mAMSA)
Year: 1983
Type: article
Abstract: Comparison of the sensitivity of DNA isolated from untreated and mAMSA-treated PY815 mouse mastocytoma cells to hydrolysis by E.coli 3'-exonuclease III and phage lambda or phage T7 5'-exonucleases show that the fragments of chromosomal DNA produced by mAMSA treatment have free 3'-OH termini and blocked 5'-termini.
Source: Nucleic Acids Research
Authors: B. Marshall, R.K. Ralph, R. Hancock
Institution: University of Auckland
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2054115024