Work

Identification of Intestinal Commensal Bacteria Protective Against GVHD in Mice and Humans

Year: 2014

Type: article

Abstract: For patients with hematologic malignancies such as leukemias, lymphomas and other related cancers, allogeneic blood/marrow transplantation (allo BMT) is a critically important therapy that can produce cures when chemotherapy alone cannot. More than 25,000 patients undergo allo BMT world-wide each year. A major risk of allo BMT continues to be graft-versus-host disease (GVHD), which results from the donor immune system recognizing the transplant recipient's organs as foreign, leading to life-threatening inflammation.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2013.12.003

Authors: Robert Jenq, Marcel R.M. van den Brink

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650