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A Lesson from “The Brodie Ultimatum”: The Locus of Control for Epilepsy is outside the Therapeutic Alliance

Year: 2013
Type: article
Abstract: Some stories are so intriguing, they must have a sequel.Some cliffhangers even need a second sequel.Professor Brodie's recent update of his ongoing prospective observational study (1) was perhaps not as eagerly anticipated as the Jason Bourne psycho-bio-über-dramas.For epilepsy watchers though, in another landmark paper, this third update (1-3) presents an ever-sharpening snapshot of the long-term course of persons diagnosed with epilepsy.And the picture is not so pretty.In the authors' epilepsy clinic, new-onset patients were treated (usually after two seizures) according to a sensible protocol of trying one antiepileptic drug (AED) followed by substitution monotherapy if the first AED was not effective or not tolerated, or by add-on therapy in the case of incomplete response to the first AED.After this initial strategy, the clinicians treated refractory patients by aiming for monotherapy but also trying polytherapy.Patients with poor adherence were excluded from the study.The outcome at last follow-up was categorized into one of four mutually exclusive groups:
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W2054630324
FWCI: 0.237
Cites: 12
Cited by: 1
Related to: 10