Work

Biosynthesis of Riboflavin. Enzymatic Deamination of 2,5-Diamino-6-hydroxy-4-ribitylaminopyrimidine-5′-phosphate

Year: 1980

Type: article

Abstract: Cell extracts of Saccharomyces cerevisiae and Candida guilliermondii catalyze the hydrolytic deamination in position 2 of 2,5-diamino-6-hydroxy-4-ribitylaminopvrimidine 5′-phosphate. The deaminase activity is absent in rib 2 mutants of S. cerevisiae. These findings confirm the biosynthetic pathway proposed earlier on the basis of metabolic and genetic studies [2].

Source: Zeitschrift für Naturforschung B

DOI: 10.1515/znb-1980-0415

Authors: Gerhard Klein, Adelbert Bacher

Institution: Technical University of Munich

Language: English

Topic: Biochemical and Molecular Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,712

Funder: Deutsche Forschungsgemeinschaft