Work

Adoptively Transferred NK Cells Home to Tumor Sites and Accumulate With Tumor Growth But Do Not Lead to Tumor Regression in a Murine B-Cell Lymphoma Model

Year: 2011

Type: article

Abstract: Natural killer (NK) cells can reject tumor in in vitro cytotoxicity experiments and in murine models where depletion of endogenous NK cells leads to accelerated tumor growth. Given that allogeneic NK cells can be safely transferred into mice and humans, it is now important to investigate whether these NK cells can home to tumor.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2010.12.510

Authors: S. Gill, M. Florek, H.E. Kohrt, R.S. Negrin

Institution: Stanford University

Language: English

Topic: Immune Cell Function and Interaction

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650