Work

Exercise Stress Testing in Recently Abstinent Chronic Cocaine Abusers

Year: 2008

Type: article

Abstract: We compared treadmill exercise stress testing (EST) in 28 medically screened, chronic cocaine users with the cardiovascular effects of an IV cocaine challenge (25 mg or 50 mg). All subjects had a clinically normal EST and echocardiography (except 2 subjects had septal wall hypokinesis). The EST produced significantly greater increases in heart rate and rate-pressure product than did the cocaine challenges. These findings suggest that EST may not provide additional diagnostic information in medically screened cocaine users. EST may cause more cardiac work (indicated by heart rate and blood pressure) than intravenous cocaine (at the doses in this study).

Source: The American Journal of Drug and Alcohol Abuse

DOI: 10.1080/00952990802082214

Authors: Praveen Kanneganti, Richard A. Nelson, Susan J. Boyd, Roy C. Ziegelstein, David A. Gorelick

Institutions: National Institutes of Health, National Institute on Drug Abuse, Johns Hopkins University

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Drug Abuse