Work

Crystal structure of human HMG-CoA lyase

Year: 2005

Type: article

Abstract: MACROMOLECULES C193wild-type UPPs and the Asp26Ala mutant are crystallized in a new trigonal unit cell with Mg 2+ /IPP/FsPP (farnesyl thiopyrophosphate, an FPP analogue) bound to the active site.Our results here improve the understanding of the prenyltransferases reaction significantly.

Source: Acta Crystallographica Section A Foundations of Crystallography

DOI: 10.1107/s0108767305091804

Authors: Z. Fu, J. A. Runquist, H. M. Miziorko, J.-J. P. Kim

Institutions: Medical College of Wisconsin, University of Missouri–Kansas City

Language: English

Topic: Enzyme Structure and Function

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2056294307

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