Work

The concept of translocational regulation

Year: 2008

Type: review

Abstract: Biological processes are regulated to provide cells with exquisite adaptability to changing environmental conditions and cellular demands. The mechanisms regulating secretory and membrane protein translocation into the endoplasmic reticulum (ER) are unknown. A conceptual framework for translocational regulation is proposed based on our current mechanistic understanding of ER protein translocation and general principles of regulatory control.

Source: The Journal of Cell Biology

DOI: 10.1083/jcb.200804157

Authors: Ramanujan S. Hegde, Sang-Wook Kang

Institutions: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Language: English

Topic: Cellular transport and secretion

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institutes of Health

OpenAlex ID: W2056502129

FWCI: 1.269

Cites: 76

Cited by: 122

Related to: 10