Work

Effects of the serotonin reuptake inhibitor fluvoxamine on yohimbine-induced anxiety in panic disorder

Year: 1993

Type: article

Abstract: To assess the effects of the selective serotonin reuptake blocker fluvoxamine on noradrenergic function in patients with panic disorder, an intravenous yohimbine challenge test was administered to eight patients with panic disorder before and after 8 weeks of fluvoxamine treatment and to a parallel group of eight patients treated with placebo. Fluvoxamine treatment reduced yohimbine-induced anxiety while placebo treatment had no effect on this variable. Both fluvoxamine and placebo treatment had little effect on biochemical or physiologic responses to yohimbine.

Source: Psychiatry Research

DOI: 10.1016/0165-1781(93)90036-g

Authors: Andrew W. Goddard, Scott W. Woods, Diane E. Sholomskas, Wayne K. Goodman, Dennis S. Charney, George R. Heninger

Institutions: Yale University, Connecticut Mental Health Center, VA Connecticut Healthcare System

Language: English

Topic: Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Subfield: Experimental and Cognitive Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,230