Year: 1998
Type: article
Abstract: The successfuIl testing and cLevelopment of a new live, attenuated mutant (s) o/S. typhi as a typhoid vaccine creates an oPportutlity for eleveloping novel bivalent or multivalent human vaccines. Development of such vaccines wiIL require careful analysis of optimal ex- pression system (gene closage, promoter strength,...) to ensLtre that the recombinant S. typhi elicit a maximal response against the co-ex- pressecL heterologous antigen. We have ntodelled the construction of bivalent vaccines ln S. typhimurium uslng the murine model of 'typhoid
Source: Medical Journal of Indonesia
Authors: S.J. Dunstan, C.P. Simmons, R.A. Strugnell
Institution: The University of Melbourne
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $300
OpenAlex ID: W2056596729