Qualitative changes of drug resistant bacteria and their conjugative R plasmids isolated in hospitals in Tokyo area.
Year: 1980
Type: article
Abstract: Changes of resistant Escherichia coli strains and their conjugative R plasmids followed by the changes of chemotherapy occurred in Japan were described. The chemotherapy in Japan has changed from parallel usages of various drugs to the extensive and high dose usages of β-lactam antibiotics after 1975. As expected, β-lactam antibiotic resistant strains increased great-ly. But conjugative R plasmids have had rather qualitative changes, that is, conjugative R plasmids seemed to receive rearrangements of their genes and become fewer drug resistant forms or non (less) -conjugative forms from multiple drug resistant conjugative forms.
Source: The Keio Journal of Medicine
DOI: 10.2302/kjm.29.185
Authors: TOSHIHIKO ARAI, SADAO KOMATSU, YOKO KOMATSU, AKIO KOBAYASHI
Institutions: Keio University, Chiba University Hospital
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2056695146