Work

Quantitative modeling of the behaviour of microfluidic autoregulatory devices

Year: 2012

Type: article

Abstract: We develop a theoretical model for a fluidic current source consisting of a via, a detour channel, and a push-up type micro-valve. The model accurately describes the non-linear behaviour of this type of device, which has been previously measured experimentally. We show how various structural parameters and material properties of the device influence the saturated flow rate and the minimum driving pressure required for the device to function as a current source. Conversely, the model can be used to design a fluidic current source with a desired saturated flow rate and low operational pressure. The present model can be straightforwardly applied to microfluidic circuits composed of many functional autoregulatory devices.

Source: Lab on a Chip

DOI: 10.1039/c2lc20956j

Authors: Hyun-Joo Chang, Wubing Ye, Emil P. Kartalov

Institutions: University of Southern California, California Institute of Technology

Language: English

Topic: Microfluidic and Capillary Electrophoresis Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering

Award: Integrated Nanofluidic BioMEMS for Biomedical Diagnostics and Analysis