Work

Exercise Physiology versus Inactivity Physiology: An Essential Concept for Understanding Lipoprotein Lipase Regulation

Year: 2004

Type: article

Abstract: In Brief HAMILTON, M.T., D.G. HAMILTON, and T.W. ZDERIC. Exercise physiology versus inactivity physiology: An essential concept for understanding lipoprotein lipase regulation. Exerc. Sport Sci. Rev., Vol. 32, No. 4, pp. 161–166, 2004. Some health-related proteins such as lipoprotein lipase may be regulated by qualitatively different processes over the physical activity continuum, sometimes with very high sensitivity to inactivity. The most powerful process known to regulate lipoprotein lipase protein and activity in muscle capillaries may be initiated by inhibitory signals during physical inactivity, independent of changes in lipoprotein lipase messenger RNA. Some health-promoting proteins like lipoprotein lipase may be regulated by qualitatively different processes over the physical activity continuum, with high sensitivity to inactivity.

Source: Exercise and Sport Sciences Reviews

DOI: 10.1097/00003677-200410000-00007

Authors: Marc T. Hamilton, Deborah G. Hamilton, Theodore W. Zderic

Institution: University of Missouri

Language: English

Topic: Lipid metabolism and disorders

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases